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Dehydroepiandrosterone (DHEA)
DHEA is the most prevalent of the hormones produced by the adrenal glands. After being secreted by the adrenal glands, it circulates in the bloodstream as DHEA-sulfate (DHEAS) and is converted as needed into other hormones. Supplementation with DHEAS has resulted in increased levels of testosterone and androstenedione, two steroid hormones. The FDA banned the sale of DHEA as a therapeutic drug in 1996 until its safety and value could be reviewed. DHEA products on the market as dietary supplements are regulated under a 1994 law, the dietary supplement health and education act (DSHEA). Although it is difficult to show clear side effects from DHEA supplements, several publications have raised concerns regarding altered hormone profiles, liver abnormalities, increased cancer risk (prostate in men and breast in women), and other steroid-like effects (increased facial hair, acne, mood swings). Since DHEA is converted into testosterone, there have been concerns that chronic use in men might worsen prostate hyperplasia or even promote prostate cancer
DHEA is the most prevalent of the hormones produced by the adrenal glands. After being secreted by the adrenal glands, it circulates in the bloodstream as DHEA-sulfate (DHEAS) and is converted as needed into other hormones. Supplementation with DHEAS has resulted in increased levels of testosterone and androstenedione, two steroid hormones. The FDA banned the sale of DHEA as a therapeutic drug in 1996 until its safety and value could be reviewed. DHEA products on the market as dietary supplements are regulated under a 1994 law, the dietary supplement health and education act (DSHEA). Although it is difficult to show clear side effects from DHEA supplements, several publications have raised concerns regarding altered hormone profiles, liver abnormalities, increased cancer risk (prostate in men and breast in women), and other steroid-like effects (increased facial hair, acne, mood swings). Since DHEA is converted into testosterone, there have been concerns that chronic use in men might worsen prostate hyperplasia or even promote prostate cancer
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